Rawsonol

Catalog No.: A75690
HMG-CoA Reductase (HMGCR) Inhibitor
Rawsonol is a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, a key enzyme in the cholesterol biosynthesis pathway. Derived from the green alga Avrainuika rawsoni, Rawsonol demonstrates significant inhibitory activity, making it a valuable tool for research investigating cholesterol regulation and related metabolic pathways. Its role as an HMGCR inhibitor positions it for applications in studies of lipid metabolism and cardiovascular health.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRawsonol is a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, a key enzyme in the cholesterol biosynthesis pathway. Derived from the green alga Avrainuika rawsoni, Rawsonol demonstrates significant inhibitory activity, making it a valuable tool for research investigating cholesterol regulation and related metabolic pathways. Its role as an HMGCR inhibitor positions it for applications in studies of lipid metabolism and cardiovascular health.
Product Information
Catalog NumA75690
FormulaC29H24Br4O7
Molecular Weight804.11
CAS Number125111-69-5
SMILESOC1=C(Br)C=C(COC)C(CC2=CC(CC3=CC(Br)=C(O)C(O)=C3CC4=CC=C(O)C(Br)=C4)=C(O)C(Br)=C2)=C1O
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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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