Raxlaprazine etomoxil

Catalog No.: A60004
Dopamine Receptor Modulator
Raxlaprazine etomoxil is a small molecule compound that functions as a dopamine D2 and D3 receptor modulator. This compound shows high affinity for human recombinant D2L receptors, with an inhibition constant (Ki) of 1.95 nM, and effectively inhibits forskolin-stimulated cAMP accumulation with a half maximal effective concentration (EC50) of 3.72 nM. Raxlaprazine etomoxil is valuable for research focused on mental illnesses and neurological disorders.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRaxlaprazine etomoxil is a small molecule compound that functions as a dopamine D2 and D3 receptor modulator. This compound shows high affinity for human recombinant D2L receptors, with an inhibition constant (Ki) of 1.95 nM, and effectively inhibits forskolin-stimulated cAMP accumulation with a half maximal effective concentration (EC50) of 3.72 nM. Raxlaprazine etomoxil is valuable for research focused on mental illnesses and neurological disorders.
Product Information
Catalog NumA60004
FormulaC23H36Cl2N4O2
Molecular Weight471.46
CAS Number3034857-88-7
SMILESClC1=C(C=CC=C1Cl)N2CCN(CC2)CC[C@H]3CC[C@@H](CC3)NC(N(C)COCC)=O
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