Fig. 1 · Structure
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Raxofelast
Antioxidant Agent
Raxofelast is an antioxidant agent known for its protective role in models of ischemia-reperfusion injury. It exhibits antiproliferative activity in hydrogen peroxide-stimulated rat aortic smooth muscle cells by inhibiting key signaling pathways, including mitogen-activated protein kinase (MAPK), ERK kinase 1 and 2 (MEK1,2), and protein kinase C (PKC), while leaving Ras expression unaffected. This compound is valuable for research applications aimed at understanding oxidative stress and related vascular pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 128232-14-4 |
| Applications | Antioxidant Agent |
| Formula | C15H18O5 |
| Molecular Weight | 278.30 |
| Synonyms | IRFI-016 |
| SMILES | O=C(CC1OC2=C(C1)C(C)=C(OC(C)=O)C(C)=C2C)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.