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RBN-3143

Catalog No.: A29092
PARP14 Inhibitor
RBN-3143 is a potent NAD+-competitive inhibitor of PARP14, exhibiting an IC50 of 4 nM. This compound effectively inhibits PARP14-mediated ADP-ribosylation and stabilizes the enzyme in cellular contexts. RBN-3143 is ideal for investigating the role of PARP14 in lung inflammation and other related research applications.
RBN-3143 2360853-16-1 PARP14 Inhibitor
Grouped product items
Size Price Stock Qty
1mg
$45.00
In stock
5mg
$115.00
In stock
10mg
$185.00
In stock
25mg
$375.00
In stock
50mg
$550.00
In stock
100mg
$790.00
In stock
200mg
$1,035.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRBN-3143 is a potent NAD+-competitive inhibitor of PARP14, exhibiting an IC50 of 4 nM. This compound effectively inhibits PARP14-mediated ADP-ribosylation and stabilizes the enzyme in cellular contexts. RBN-3143 is ideal for investigating the role of PARP14 in lung inflammation and other related research applications.
Product Information
Catalog NumA29092
FormulaC22H28FN3O4S
Molecular Weight449.54
CAS Number2360853-16-1
SMILESO=C1NC(CSC2CCOCC2)=NC3=CC(OCC4CCN(CC4)C(C)=O)=CC(F)=C13
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Epigenetics > PARP
DNA Damage > PARP