Fig. 1 · Structure
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RBP4 inhibitor 1
RBP4 Inhibitor
RBP4 Inhibitor 1 is a potent and orally active inhibitor of retinol-binding protein 4 (RBP4), exhibiting IC50 values of 28 nM and 110 nM for human and mouse RBP4, respectively. This compound effectively reduces blood RBP4 levels in mice, demonstrating significant biological activity in the modulation of metabolic pathways associated with obesity and insulin resistance. RBP4 Inhibitor 1 is valuable for researchers investigating the role of RBP4 in metabolic diseases and related therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1198180-03-8 |
| Applications | RBP4 Inhibitor |
| Formula | C14H13F6NO3 |
| Molecular Weight | 357.25 |
| SMILES | O=C(O)CO[C@@H]1CN(C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.