Fig. 1 · Structure
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RBPJ Inhibitor-1
RBPJ Inhibitor
RBPJ Inhibitor-1 (RIN1) is a potent inhibitor of RBPJ, targeting the functional interaction between RBPJ and SHARP. This compound effectively inhibits NOTCH-dependent tumor cell proliferation, making it a valuable tool for research into NOTCH signaling pathways and their role in cancer biology. RBPJ Inhibitor-1 is particularly relevant for studies investigating therapeutic strategies in tumors characterized by aberrant NOTCH signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2682114-39-0 |
| Applications | RBPJ Inhibitor |
| Formula | C17H14FN3O2 |
| Molecular Weight | 311.31 |
| Synonyms | RIN1 |
| SMILES | O=C(N)C1=CC=C(C2=CC=NN2C)C=C1OC3=CC=CC=C3F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.