Fig. 1 · Structure
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Rebamipide mofetil
Rebamipide Prodrug
Rebamipide mofetil is an orally active prodrug of Rebamipide, which serves as a mucoprotective agent. It increases the expression of COX-2 and elevates levels of prostaglandin E2 (PGE2), thereby enhancing gastric mucosal defense through a COX-2-dependent mechanism. This compound is primarily utilized in research related to gastrointestinal protection and the modulation of inflammatory processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1527495-76-6 |
| Applications | Rebamipide Prodrug |
| Formula | C25H26ClN3O5 |
| Molecular Weight | 483.94 |
| SMILES | O=C1C=C(CC(C(OCCN2CCOCC2)=O)NC(C3=CC=C(C=C3)Cl)=O)C4=C(N1)C=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.