Fig. 1 · Structure
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Rebamipide
Gastroprotective Agent
Rebamipide is an orally active gastroprotective agent primarily targeting the enhancement of endogenous prostaglandin (PG) production, particularly intragastric PGE2, through the induction of COX-2 expression. This compound plays a crucial role in protecting the gastric mucosa from injury and demonstrates anti-proliferative activity against gastric cancer cells. Rebamipide is valuable for research applications concerning mucosal protection, gastroduodenal ulcers, gastritis, and gastric cancer.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 90098-04-7 |
| Applications | Gastroprotective Agent |
| Formula | C19H15ClN2O4 |
| Molecular Weight | 370.79 |
| Synonyms | OPC12759; Proamipide |
| SMILES | OC(C(NC(C1=CC=C(Cl)C=C1)=O)CC(C2=CC=CC=C2N3)=CC3=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.