Fig. 1 · Structure

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RECTAS-2.0

RNA mis-splicing Corrector

RECTAS-2.0 is a small molecule targeted at correcting RNA mis-splicing associated with the GLA c.639+919G>A mutation. It has demonstrated potential in restoring normal splicing patterns, thereby offering a strategic approach for studying Fabry disease. This reagent is particularly relevant for researchers investigating therapeutic interventions aimed at genetic disorders linked to splicing abnormalities.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 3038234-95-3
Applications RNA mis-splicing Corrector
Formula C18H17ClN4O4
Molecular Weight 388.80
SMILES
ClC1=NC(C(OC[C@H]2CN(C)C(O2)=O)=NC=C3)=C3C(NCC4=CC=CO4)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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