Fig. 1 · Structure
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rel-(2S,3R)-Voruciclib hydrochloride
CDK
rel-(2S,3R)-Voruciclib hydrochloride is the rel-(2S,3R)-enantiomer of Voruciclib, a potent inhibitor of cyclin-dependent kinases (CDKs). This compound exhibits significant biological activity in regulating cell cycle progression and has potential applications in cancer research, particularly in therapeutic strategies targeting CDK-mediated pathways. Its oral bioavailability makes it a valuable tool for in vivo studies of cell proliferation and tumor growth.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1253647-46-9 |
| Applications | CDK |
| Formula | C22H20Cl2F3NO5 |
| Molecular Weight | 506.30 |
| SMILES | ClC1=CC(C(F)(F)F)=CC=C1C(OC2=C(C(O)=CC(O)=C23)[C@H]([C@H]4CO)CCN4C)=CC3=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.