Fig. 1 · Structure
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Reldesemtiv
Fast Skeletal Muscle Troponin Activator
Reldesemtiv is a selective fast skeletal muscle troponin activator, designed to enhance contractile function in fast-twitch myofibrils. With an EC50 of 3.4 μM, it demonstrates significant biological activity in improving muscle performance. Reldesemtiv is primarily utilized in research applications related to muscle physiology and heart failure models, offering insights into therapeutic strategies for conditions characterized by muscle weakness and reduced exercise capacity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1345410-31-2 |
| Applications | Fast Skeletal Muscle Troponin Activator |
| Formula | C19H18F2N6O |
| Molecular Weight | 384.38 |
| Synonyms | CK-2127107 |
| SMILES | O=C(C1=CN(C2=CN=C(NC[C@]3(C4=NC=CC=C4F)C[C@H](F)C3)N=C2)C=C1)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.