Renadirsen

Catalog No.: A57375
Dystrophin exon 45 skipping antisense oligonucleotide
Renadirsen is an antisense oligonucleotide designed to promote exon 45 skipping of the dystrophin gene. This mechanism facilitates the production of a functional dystrophin protein, which is crucial for muscle function. Renadirsen is primarily utilized in research related to Duchenne muscular dystrophy (DMD), aiming to advance therapeutic strategies targeting dystrophinopathies.
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRenadirsen is an antisense oligonucleotide designed to promote exon 45 skipping of the dystrophin gene. This mechanism facilitates the production of a functional dystrophin protein, which is crucial for muscle function. Renadirsen is primarily utilized in research related to Duchenne muscular dystrophy (DMD), aiming to advance therapeutic strategies targeting dystrophinopathies.
Product Information
Catalog NumA57375
CAS Number1782108-31-9
SMILES[Renadirsen]
SynonymsDS-5141b
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