Fig. 1 · Structure

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Renadirsen

Dystrophin exon 45 skipping antisense oligonucleotide

Renadirsen is an antisense oligonucleotide designed to promote exon 45 skipping of the dystrophin gene. This mechanism facilitates the production of a functional dystrophin protein, which is crucial for muscle function. Renadirsen is primarily utilized in research related to Duchenne muscular dystrophy (DMD), aiming to advance therapeutic strategies targeting dystrophinopathies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1782108-31-9
Applications Dystrophin exon 45 skipping antisense oligonucleotide
Synonyms DS-5141b

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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