Fig. 1 · Structure
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Renzapride hydrochloride
5-HT Receptor
Renzapride hydrochloride is a benzamide derivative primarily targeting 5-HT receptors. It exhibits antagonistic activity at 5-HT(3) receptors and agonistic activity at 5-HT(4) receptors, which contributes to its efficacy in treating irritable bowel syndrome. Additionally, Renzapride hydrochloride shows antagonistic properties at 5-HT(2B) receptors and demonstrates significant affinity for 5-HT(2A) and 5-HT(2C) receptors, making it a valuable tool in gastrointestinal research and the study of serotonin receptor mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 109872-41-5 |
| Applications | 5-HT Receptor |
| Formula | C16H23Cl2N3O2 |
| Molecular Weight | 360.28 |
| SMILES | ClC1=C(N)C=C(OC)C(C(N[C@H]2CCN3CCC[C@@H]2C3)=O)=C1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.