Fig. 1 · Structure
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Resolvin D1
Endogenous Inflammation Mediator
Resolvin D1 (RvD1) is an endogenous pro-resolving mediator of inflammation derived from omega-3 docosahexaenoic acid, playing a crucial role in the resolution phase of acute inflammation. RvD1 effectively inhibits pro-inflammatory neutrophil migration by regulating actin polymerization, diminishes TNF-α-mediated inflammation in macrophages, and promotes the phagocytosis of apoptotic cells by macrophages. This compound is instrumental in studying inflammation resolution mechanisms and potential therapeutic interventions for inflammatory disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 872993-05-0 |
| Applications | Endogenous Inflammation Mediator |
| Formula | C22H32O5 |
| Molecular Weight | 376.49 |
| Synonyms | RvD1 |
| SMILES | CC/C=C\C[C@@H](/C=C/C=C\C=C\C=C\[C@H]([C@H](C/C=C\CCC(O)=O)O)O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.