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Resolvin D5 n-3 DPA

Specialized Proresolving Lipid Mediator

Resolvin D5 n-3 DPA is a specialized proresolving lipid mediator derived from docosapentaenoic acid. It acts as an agonist for GPR101, GPR12, and GPR84, displaying EC50 values of 4.6 pM, 14 pM, and 1.5 pM, respectively. This compound exhibits potent anti-inflammatory and pro-resolution properties, effectively reducing cell adhesion on TNF-α-activated human endothelial monolayers. Furthermore, Resolvin D5 n-3 DPA enhances leukocyte functions, promoting the phagocytic activity of neutrophils and macrophages, making it valuable in research related to intestinal inflammation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	1609382-32-2
Applications	Specialized Proresolving Lipid Mediator
Formula	C₂₂H₃₄O₄
Molecular Weight	362.51
SMILES	[C@@H](/C=C/C=C\C/C=C\C=C\[C@H](C/C=C\CC)O)(CCCCCC(O)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.