RET-IN-1

Name: RET-IN-1
Brand: Adooq Bioscience
SKU: A19015
Rating: 5 (288 reviews)

Catalog No.: A19015

RET inhibitor

RET-IN-1 is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 552, has IC50s of 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively .

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Grouped product items
Size	Price	Stock
1mg	$315.00	In stock
5mg	$955.00	In stock
10mg	$1,595.00	In stock
25mg	$2,565.00	In stock
50mg	$3,375.00	In stock
100mg	$4,595.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	RET-IN-1 is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 552, has IC50s of 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively .

Product Information

Catalog Num	A19015
Formula	C29H31N9O3
Molecular Weight	553.61
CAS Number	2222755-14-6
SMILES	N#CC1=C2C(C3=NC=C(N4CC(C5)N(CC6=CC=C(OC)N=C6)C5C4)N=C3)=CC(OC[C@H]7CNCCO7)=CN2N=C1
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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