Fig. 1 · Structure
Documents & Downloads
RET-IN-24
RET Inhibitor
RET-IN-24 is a selective inhibitor of the RET tyrosine kinase, demonstrating significant antitumor activity. This compound is valuable in research focused on targeting RET-related signaling pathways in cancer, contributing to the understanding of tumorigenesis and potential therapeutic strategies. Its specificity allows for detailed investigations into RET-dependent malignancies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2583767-68-2 |
| Applications | RET Inhibitor |
| Formula | C27H26F2N8O |
| Molecular Weight | 516.55 |
| SMILES | N#CC1=C2C(C3=CC=C(N4CCN(CC4)CC5=CN=C(C=C5)OC)N=C3)=CC(N6CC(F)(C6)F)=CN2N=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.