Fig. 1 · Structure

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RET-IN-30

RET Inhibitor

RET-IN-30 is a selective RET inhibitor, targeting both wild-type RET and several of its mutant forms. This compound demonstrates significant anti-proliferative activity in A549 cancer cells, highlighting its potential as an anti-tumor agent. RET-IN-30 is valuable for research focused on RET-related signaling pathways and targeted therapies in oncology.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3081389-07-0
Applications RET Inhibitor
Formula C26H26FN5O
Molecular Weight 443.52
SMILES
FC1=CC(OC2CN(C2)C3=NC=C(C=C3)C4=C5N=CC=NC5=CC(N(CC)CC)=C4)=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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