Fig. 1 · Structure
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RET-IN-8
RET Inhibitor
RET-IN-8 is a selective inhibitor of the rearranged during transfection (RET) kinase, providing a valuable tool for cancer research. By targeting RET, this compound disrupts oncogenic signaling pathways associated with various malignancies. Its application in studying RET-driven tumors may facilitate the development of targeted therapies and enhance understanding of RET-related pathophysiology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2642164-75-6 |
| Applications | RET Inhibitor |
| Formula | C27H30N6O3 |
| Molecular Weight | 486.57 |
| SMILES | N#CC1=C2C(C3=CC=C(N4CCN(C([C@H](O)C(C)C)=O)CC4)N=C3)=CC(C5=CCOCC5)=CN2N=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.