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RET ligand-1

Target Protein Ligand

RET Ligand-1 is a ligand specifically designed to interact with the RET proto-oncogene receptor tyrosine kinase. This compound can be utilized in the synthesis of bifunctional molecules, such as PROTAC LDD39, for targeted protein degradation studies. Its ability to modulate RET signaling pathway has implications in cancer research and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3028787-16-5
Applications	Target Protein Ligand
Formula	C₂₈H₂₄F₂N₆O₃
Molecular Weight	530.53
SMILES	CCOC1=CN2N=CC(C#N)=C2C(C3=CN=C(N4CCC(C=O)(CC4)NC(C5=C(F)C=CC(F)=C5)=O)C=C3)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.