Fig. 1 · Structure

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RET ligand-5

PROTAC RET Ligand

RET ligand-5 is a PROTAC target protein ligand aimed at facilitating the synthesis of PROTACs, such as PROTAC RET Degrader 1. This compound exhibits potent RET degradation capabilities, showcasing significant anti-tumor activity. Its application in research is critical for studies focused on targeted protein degradation and cancer therapeutics.

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Specifications

Manufacturer Adooq Bioscience
Actions Degrader
CAS Number 2760853-48-1
Applications PROTAC RET Ligand
Formula C23H26ClN7O
Molecular Weight 451.95
SMILES
CCC1(CCN(CC1)C2=NC=C(C=C2)C3=NC(Cl)=CN4N=CC(C#N)=C34)C(NC(C)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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