Fig. 1 · Structure

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Retinoic acid-d3-1

Stable Isotope

Retinoic acid-d3-1 is a deuterium-labeled derivative of retinoic acid, a vital metabolite of vitamin A. This compound acts as a natural agonist for retinoic acid receptors (RARs), demonstrating inhibitory effects on transcription factor Nrf2 while also engaging peroxisome proliferator-activated receptor beta/delta (PPARβ/δ) with a Kd of 17 nM. Retinoic acid is integral to various biological processes, including cell growth, differentiation, and organogenesis, making it valuable for research in developmental biology and therapeutic studies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 3041101-53-2
Applications Stable Isotope
Formula C20H25D3O2
Molecular Weight 303.45
Synonyms Vitamin A acid-d3-1; all-trans-Retinoic acid-d3-1; ATRA-d3-1
SMILES
CC(/C=C/C1=C(CCCC(C)1C)C)=C\C=C\C(C([2H])([2H])[2H])=C\C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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