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Retro-1

Toxin Inhibitor

Retro-1 is a potent toxin inhibitor that specifically blocks the retrograde transport of Shiga toxin B (STxB) to the trans-Golgi network. This compound effectively mitigates the cytotoxic effects of Ricin and bacterial toxins Stx1 and Stx2. Additionally, Retro-1 enhances the efficacy of antisense and splice-switching oligonucleotides, making it a valuable tool for research in toxin biology and therapeutic applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	313683-81-7
Applications	Toxin Inhibitor
Formula	C₁₈H₁₇BrN₂O₂
Molecular Weight	373.24
SMILES	O=C1NC2=CC=C(C=C2C(N(C1)C(CC)=O)C3=CC=CC=C3)Br

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.