Fig. 1 · Structure
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Rev1-CT/RIR PPI-IN-1
Rev1-CT/RIR Interaction Inhibitor
Rev1-CT/RIR PPI-IN-1 is a thiophene-based compound that specifically inhibits the interaction between Rev1-CT and RIR, exhibiting an IC50 value of 2.5 µM. This compound enhances chemosensitivity and decreases the mutation rate in Cisplatin-sensitive HT-1080 cells, making it a valuable tool for cancer research. Rev1-CT/RIR PPI-IN-1 is suitable for studies investigating mechanisms of tumor resistance and therapeutic efficacy.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 908510-73-6 |
| Applications | Rev1-CT/RIR Interaction Inhibitor |
| Formula | C21H29N3O3S |
| Molecular Weight | 403.54 |
| SMILES | O=C(C1CCN(C(C)=O)CC1)NC2=C(C(NC3CC3)=O)C(CCC(C)C4)=C4S2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.