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Revospirone

Catalog No.: A29444
5-HT1A receptor partial Agonist
Revospirone is a partial agonist of the 5-HT1A receptor, exhibiting a Ki value of 2 nmol/L. This compound effectively inhibits adenylate cyclase activity with an IC50 of 124 nmol/L. Revospirone is utilized in research applications targeting neuropharmacology and may aid in studying anxiety and mood disorders through its influence on serotonergic signaling pathways.
Revospirone 95847-87-3 5-HT1A receptor partial Agonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRevospirone is a partial agonist of the 5-HT1A receptor, exhibiting a Ki value of 2 nmol/L. This compound effectively inhibits adenylate cyclase activity with an IC50 of 124 nmol/L. Revospirone is utilized in research applications targeting neuropharmacology and may aid in studying anxiety and mood disorders through its influence on serotonergic signaling pathways.
Product Information
Catalog NumA29444
FormulaC18H21N5O3S
Molecular Weight387.46
CAS Number95847-87-3
SMILESO=C1C2=C(S(=O)(N1CCCN3CCN(CC3)C4=NC=CC=N4)=O)C=CC=C2
SynonymsBAY Vq 7813
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GPCR/G Protein > 5-HT Receptors