Fig. 1 · Structure

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RG 13647

AT2 Ligand

RG 13647 is an AT2-selective ligand that serves as an analog of PD 123177. This compound demonstrates weak competition for [125I]angiotensin II binding, with an IC50 value of 100 μM. RG 13647 is primarily utilized in cardiovascular disease research, facilitating investigations into the role of angiotensin II receptors in related pathophysiological conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 145543-03-9
Applications AT2 Ligand
Formula C30H27N3O5
Molecular Weight 509.55
SMILES
O=C(O)C1CC2=C(CN1C(C(C3=CC=CC=C3)C4=CC=CC=C4)=O)N=CN2CC5OC6=CC=CC=C6OC5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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