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RGH-122

V1a Receptor Antagonist

RGH-122 is a selective antagonist of the human V1a receptor, exhibiting high potency with a Ki value of 0.3 nM and an IC50 of 0.9 nM. This compound demonstrates favorable microsomal stability, with a clearance rate (CLint) of 13/28/25 μL/min/mg. RGH-122 is valuable for research applications involving vasopressin receptor signaling and related pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	2355304-05-9
Applications	V1a Receptor Antagonist
Formula	C₂₄H₂₅ClN₄O₃
Molecular Weight	452.93
SMILES	ClC1=CC=[C@]2[N@]3C([C@H](CC4)CC[C@@H]4OC5=NC=CC=C5)=NN=C3CC6(OCCO6)CC2=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.