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RGH-560

α7 nAChR Modulator

RGH-560 is a positive modulator of the α7 nicotinic acetylcholine receptor (nAChR), known for its advanced pharmacological properties and favorable physicochemical characteristics. This compound exhibits significant procognitive effects in vivo, making it a valuable tool for studying cognitive enhancement. RGH-560 is particularly useful in researching scopolamine-induced amnesia in murine models, providing insights into memory and learning processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Modulator
CAS Number	2408799-43-7
Applications	α7 nAChR Modulator
Formula	C₂₂H₂₀FN₃O₃
Molecular Weight	393.41
SMILES	CN1C=CC2=C1C=CC(CNC(N3CC4(CC(C(C=CC(F)=C5)=C5O4)=O)C3)=O)=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.