RGH-560

Catalog No.: A67677
α7 nAChR Modulator
RGH-560 is a positive modulator of the α7 nicotinic acetylcholine receptor (nAChR), known for its advanced pharmacological properties and favorable physicochemical characteristics. This compound exhibits significant procognitive effects in vivo, making it a valuable tool for studying cognitive enhancement. RGH-560 is particularly useful in researching scopolamine-induced amnesia in murine models, providing insights into memory and learning processes.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRGH-560 is a positive modulator of the α7 nicotinic acetylcholine receptor (nAChR), known for its advanced pharmacological properties and favorable physicochemical characteristics. This compound exhibits significant procognitive effects in vivo, making it a valuable tool for studying cognitive enhancement. RGH-560 is particularly useful in researching scopolamine-induced amnesia in murine models, providing insights into memory and learning processes.
Product Information
Catalog NumA67677
FormulaC22H20FN3O3
Molecular Weight393.41
CAS Number2408799-43-7
SMILESCN1C=CC2=C1C=CC(CNC(N3CC4(CC(C(C=CC(F)=C5)=C5O4)=O)C3)=O)=C2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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