RGT-018

Name: RGT-018
Brand: Adooq Bioscience
SKU: A24227
Rating: 5 (288 reviews)

Catalog No.: A24227

SOS1 inhibitor

RGT-018 is a potent, orally active SOS1 inhibitor that exhibits anti-tumor activity by blocking KRAS activation. By disrupting the SOS1–KRAS interaction, RGT-018 effectively inhibits cancer cell proliferation, making it a promising candidate for targeting KRAS-driven malignancies.

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Grouped product items
Size	Price	Stock
1mg	$72.00	In stock
5mg	$216.00	In stock
10mg	$368.00	In stock
50mg	$1,104.00	In stock
Bulk Size	Bulk Discount

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Research use only. We do not sell to patients.

Data Sheet SDS

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Adooq Products cited in reputable paper

Biological Activity

Description	RGT-018 is a potent, orally active SOS1 inhibitor that exhibits anti-tumor activity by blocking KRAS activation. By disrupting the SOS1–KRAS interaction, RGT-018 effectively inhibits cancer cell proliferation, making it a promising candidate for targeting KRAS-driven malignancies.

Product Information

Catalog Num	A24227
Formula	C27H24F3N7O2
Molecular Weight	535.52
CAS Number	2794934-49-7
SMILES	O=C1C(C2=CN=C(C#N)C=C2)=C3C(C(N[C@@H](C4=C(C(C(F)F)=CC=C4)F)C)=NC(C)=N3)=CN1N5CCOCC5
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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