Fig. 1 · Structure
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Rho-Kinase-IN-3
Rho Kinase Inhibitor
Rho-Kinase-IN-3 is a potent and selective inhibitor of Rho kinase (ROCK1) with an IC50 value of 8 nM. This compound effectively interferes with Rho kinase activity, making it valuable for studies related to hypertension and other vascular disorders. Its specificity and efficacy enable detailed investigations into the role of Rho signaling in various biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 864082-23-5 |
| Applications | Rho Kinase Inhibitor |
| Formula | C24H20N4O2 |
| Molecular Weight | 396.44 |
| SMILES | O=C(NC1=CC2=C(C=C1)NN=C2)C(C(CC3=O)C4=CC=C5C=CC=CC5=C4)=C(N3)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.