Fig. 1 · Structure

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Rhodblock 1a

Rho Kinase Signaling Pathway Inhibitor

Rhodblock 1a is a potent inhibitor of the Rho kinase signaling pathway. It disrupts the localization and function of Rho pathway proteins, impairing the formation of the cleavage furrow during cell division. As a result, Rhodblock 1a can induce the formation of binucleated cells, making it a valuable tool for investigating mechanisms of cell division. This compound holds potential for research applications in understanding diseases such as cardiovascular disorders and cancer.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 701226-08-6
Applications Rho Kinase Signaling Pathway Inhibitor
Formula C20H16N2O2
Molecular Weight 316.35
SMILES
O=C(N1N=C(C2=CC=CC=C2)CC1C3=CC=CC=C3)C4=CC=CO4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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