Fig. 1 · Structure

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Ribociclib acetate

Drug degradation products

Ribociclib acetate is a degradation product of Ribociclib, primarily formed under acid-base hydrolysis conditions. This compound has been identified as potentially carcinogenic, which underscores its relevance in studies of drug safety and metabolic pathways. Its characterization is essential for understanding drug stability and degradation in chemical research applications.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2762182-61-4
Applications Drug degradation products
Formula C21H25N7O2
Molecular Weight 407.47
SMILES
O=C(C1=CC2=C(N1C3CCCC3)N=C(NC4=NC=C(N5CCNCC5)C=C4)N=C2)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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