Fig. 1 · Structure
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Rilopirox
Antimycotic Drug
Rilopirox is a hydroxy-pyridone compound that exhibits potent antimycotic activity through its chelating properties, which inhibit catalase and disrupt the respiratory chain. It effectively inhibits the growth of various yeast isolates, demonstrating a minimum inhibitory concentration (MIC50) of 4 μg/mL. Rilopirox is primarily utilized in research applications targeting vaginal candidiasis and oropharyngeal Candida infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 104153-37-9 |
| Applications | Antimycotic Drug |
| Formula | C19H16ClNO4 |
| Molecular Weight | 357.79 |
| Synonyms | HOE 351 |
| SMILES | O=C1C=C(C)C=C(COC2=CC=C(OC3=CC=C(Cl)C=C3)C=C2)N1O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.