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Rimigorsen

Dystrophin exon 44 skipping antisense oligonucleotide

Rimigorsen is an antisense oligonucleotide designed to induce skipping of exon 44 in the pre-mRNA of dystrophin, targeting the underlying genetic mutation associated with Duchenne muscular dystrophy (DMD). This compound effectively promotes the production of partially functional dystrophin, which is critical for muscle integrity and function. Rimigorsen is a valuable tool for research in the development of therapies aimed at treating DMD and other related neuromuscular disorders.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1196915-71-5
Applications	Dystrophin exon 44 skipping antisense oligonucleotide

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.