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RIOK2-IN-1

RIOK2 Inhibitor

RIOK2-IN-1 is a selective inhibitor of RIOK2, exhibiting a Kd of 150 nM. While it demonstrates low cellular activity with an IC50 of 14,600 nM, RIOK2 plays a significant role in ribosome maturation and cell cycle regulation, linking it to various human cancers. This compound serves as a valuable tool for researchers investigating the role of RIOK2 in tumor biology and the mechanisms of cancer progression.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1088216-72-1
Applications	RIOK2 Inhibitor
Formula	C₁₈H₁₆N₂O
Molecular Weight	276.33
SMILES	O=C(CC1=CC2=C(C=CC=C2)C=C1)NC3=NC=CC(C)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.