Fig. 1 · Structure
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RIP1 kinase inhibitor 5
RIP1 Inhibitor
RIP1 Kinase Inhibitor 5 is a selective inhibitor of receptor-interacting protein kinase 1 (RIP1), which plays a crucial role as a checkpoint kinase in regulating tumor immunity. This compound effectively suppresses necroptosis and ferroptosis, making it valuable for research in cancer biology and therapeutic strategies aimed at modulating immune responses. Its application in studying RIP1-related pathways positions it as an important tool for understanding cell death mechanisms and their implications in disease progression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2428422-17-5 |
| Applications | RIP1 Inhibitor |
| Formula | C13H17F2NO2 |
| Molecular Weight | 257.28 |
| SMILES | CCC(C)(C)C(N(CC1=CC(F)=CC(F)=C1)O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.