RIP1 kinase inhibitor 5

Catalog No.: A25252
RIP1 Inhibitor
RIP1 Kinase Inhibitor 5 is a selective inhibitor of receptor-interacting protein kinase 1 (RIP1), which plays a crucial role as a checkpoint kinase in regulating tumor immunity. This compound effectively suppresses necroptosis and ferroptosis, making it valuable for research in cancer biology and therapeutic strategies aimed at modulating immune responses. Its application in studying RIP1-related pathways positions it as an important tool for understanding cell death mechanisms and their implications in disease progression.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRIP1 Kinase Inhibitor 5 is a selective inhibitor of receptor-interacting protein kinase 1 (RIP1), which plays a crucial role as a checkpoint kinase in regulating tumor immunity. This compound effectively suppresses necroptosis and ferroptosis, making it valuable for research in cancer biology and therapeutic strategies aimed at modulating immune responses. Its application in studying RIP1-related pathways positions it as an important tool for understanding cell death mechanisms and their implications in disease progression.
Product Information
Catalog NumA25252
FormulaC13H17F2NO2
Molecular Weight257.28
CAS Number2428422-17-5
SMILESCCC(C)(C)C(N(CC1=CC(F)=CC(F)=C1)O)=O
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