Fig. 1 · Structure
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RIP1 kinase inhibitor 6
R1P1 Kinase Inhibitor
RIP1 Kinase Inhibitor 6 is a potent and selective inhibitor of receptor-interacting protein kinase 1 (RIP1), exhibiting an IC50 of less than 100 nM in human RIP1 kinase assays. This compound is valuable for studying necroptosis and cell death pathways, providing a useful tool for research into inflammatory responses and related diseases. Its selective action makes it suitable for investigating the role of RIP1 in various biological systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2428401-62-9 |
| Applications | R1P1 Kinase Inhibitor |
| Formula | C19H18F2N2O3 |
| Molecular Weight | 360.35 |
| SMILES | O=C(N1CC(C1)OC2=C(C=C(C=C2)F)F)N3[C@H](C4=CC=CC=C4)CCO3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.