Fig. 1 · Structure
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RIP1/RIP3/MLKL activator 1
RIP1/RIP3/MLKL Activator
RIP1/RIP3/MLKL Activator 1 is a potent activator that induces necroptosis via the RIP1/RIP3/MLKL signaling pathway. It demonstrates significant anti-glioma activity, making it a valuable tool in cancer research. Additionally, this compound exhibits acceptable blood-brain barrier permeability, facilitating its use in studies concerning central nervous system tumors.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 2682850-41-3 |
| Applications | RIP1/RIP3/MLKL Activator |
| Formula | C43H56N4O3 |
| Molecular Weight | 676.93 |
| SMILES | CC1=C(C(C=C2C1=CC=C3[C@]4(CC[C@]5(CC[C@@](C(NCC6=CN(N=N6)CC7=CC=C(C=C7)C(C)(C)C)=O)(CC5[C@@]4(CC[C@@]23C)C)C)C)C)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.