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RIP3 activator 1

RIP3 Activator

RIP3 Activator 1 is a potent activator of receptor-interacting protein kinase 3 (RIP3). This compound induces necroptosis by engaging the RIP3/p62/Keap1 signaling pathway and promotes the expression of phosphorylated mixed lineage kinase domain-like protein (p-MLKL). Additionally, RIP3 Activator 1 enhances autophagy, evidenced by increased levels of LC3-II and p62 protein expression. It serves as a valuable tool for studying signaling pathways related to necroptosis and autophagy in various cellular contexts.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Activator
CAS Number	1456899-52-7
Applications	RIP3 Activator
Formula	C₂₆H₅₀N₄O₃
Molecular Weight	466.70
SMILES	O[C@@H]1[C@@H](N)CO[C@H]1COCC(N=N2)=CN2CCCCCCCCCCCCCCCCCC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.