RIPK1-IN-14 is a selective inhibitor of receptor-interacting protein kinase 1 (RIPK1) with an IC50 value of 92 nM. This compound demonstrates significant anti-necroptotic effects in a necroptosis model utilizing U937 cells. RIPK1-IN-14 is applicable in research focusing on cell death mechanisms, inflammation, and neurodegenerative diseases.
RIPK1-IN-14 is a selective inhibitor of receptor-interacting protein kinase 1 (RIPK1) with an IC50 value of 92 nM. This compound demonstrates significant anti-necroptotic effects in a necroptosis model utilizing U937 cells. RIPK1-IN-14 is applicable in research focusing on cell death mechanisms, inflammation, and neurodegenerative diseases.
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