RIPK1-IN-18 sulfate hydrate

Catalog No.: A25223
RIPK1 Inhibitor
RIPK1-IN-18 sulfate hydrate is a highly selective inhibitor of receptor-interacting protein kinase 1 (RIPK1), a key regulator of cell death and inflammation. Its potent inhibitory activity makes it a valuable reagent for research focused on autoimmune diseases, providing insights into the mechanistic pathways involved in such conditions. Additionally, RIPK1-IN-18 can be used to investigate the therapeutic potential of targeting RIPK1 in various inflammatory disorders.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRIPK1-IN-18 sulfate hydrate is a highly selective inhibitor of receptor-interacting protein kinase 1 (RIPK1), a key regulator of cell death and inflammation. Its potent inhibitory activity makes it a valuable reagent for research focused on autoimmune diseases, providing insights into the mechanistic pathways involved in such conditions. Additionally, RIPK1-IN-18 can be used to investigate the therapeutic potential of targeting RIPK1 in various inflammatory disorders.
Product Information
Catalog NumA25223
FormulaC22H20F4N6O7S
Molecular Weight588.49
CAS Number2897618-64-1
SMILESO=C1C2=C(CCN1CC3=CC(OC(F)(F)F)=CC=C3F)N=CC(C4=CC5=NC(N)=NN5C=C4)=C2.O=S(O)(O)=O.O
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