RIPK1-IN-7

Catalog No.: A18940

RIPK1 inhibitor

RIPK1-IN-7

RIPK1-IN-7 Chemical Structure

CAS NO. 2300982-44-7

RIPK1-IN-7 is a potent and selective RIPK1 inhibitor with a Kd of 4 nM and an enzymatic IC50 of 11 nM. RIPK1-IN-7 exhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model.

Availability: In stock

Package Price Qty
5 mg
$360.00
10 mg
$620.00
50 mg
$1,840.00
100 mg
$3,680.00
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Biological Activity

RIPK1-IN-7 is a potent and selective RIPK1 inhibitor with a Kd of 4 nM and an enzymatic IC50 of 11 nM. RIPK1-IN-7 exhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.77 mL 103.85 mL 207.7 mL
0.5 mM 4.15 mL 20.77 mL 41.54 mL
1 mM 2.08 mL 10.38 mL 20.77 mL
5 mM 0.42 mL 2.08 mL 4.15 mL

*The above data is based on the productmolecular weight 481.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18940
Actions Inhibitor
CAS No. 2300982-44-7
Formula C25H22F3N5O2
M. Wt 481.47
Purity >98%
Synonyms 0
SMILES NC1=C2C(N(CC)C=C2C3=CC(CCN4C(CC5=CC=CC(OC(F)(F)F)=C5)=O)=C4C=C3)=NC=N1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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