RIPK3-IN-6

Catalog No.: A25181
RIPK3 Inhibitor
RIPK3-IN-6 is a type I inhibitor targeting Receptor-Interacting Serine/Threonine Kinase 3 (RIPK3), known for its role in programmed necrosis and inflammation. This compound exhibits poor selectivity across the RIPK family, particularly affecting the activity of RIPK2. It serves as a valuable tool for investigating necroptosis pathways and their implications in various diseases, providing insights into signaling processes and therapeutic targets.
Grouped product items
Size Price Stock Qty
5mg
$35.00
In stock
10mg
$50.00
In stock
25mg
$105.00
In stock
50mg
$160.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRIPK3-IN-6 is a type I inhibitor targeting Receptor-Interacting Serine/Threonine Kinase 3 (RIPK3), known for its role in programmed necrosis and inflammation. This compound exhibits poor selectivity across the RIPK family, particularly affecting the activity of RIPK2. It serves as a valuable tool for investigating necroptosis pathways and their implications in various diseases, providing insights into signaling processes and therapeutic targets.
Product Information
Catalog NumA25181
FormulaC21H17N3O
Molecular Weight327.38
CAS Number955879-75-1
SMILESOC1=CC=C(C)C(NC2=CC=NC3=CC(C4=NC=CC=C4)=CC=C23)=C1
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