Fig. 1 · Structure
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Risperidone-d6
Deuterated compound
Risperidone-d6 is a deuterated analog of Risperidone, primarily functioning as a serotonin 5-HT2 receptor blocker and a dopamine D2 receptor antagonist. It demonstrates potent inhibition of both receptors, with Kis of 4.8 nM for 5-HT2A and 5.9 nM for dopamine D2. This compound is widely used in pharmacological studies and metabolic research to investigate the pharmacokinetics and dynamics of antipsychotic medications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1225444-65-4 |
| Applications | Deuterated compound |
| Formula | C23H21D6FN4O2 |
| Molecular Weight | 416.52 |
| Synonyms | R 64 766-d6 |
| SMILES | [2H]C([2H])(C1=C(C(N2CCCC([2H])(C2=N1)[2H])=O)CCN3CCC(CC3)C4=NOC5=C(C(F)=CC=C45)[2H])[2H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.