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$0.00 Biological Activity
Risperidone(Risperdal) is an atypical antipsychotic used to treat schizophrenia (including adolescent schizophrenia), schizoaffective disorder, the mixed and manic states associated with bipolar disorder, and irritability in children with autism.
Targets
| Target | Value |
|---|---|
| 5-HT2A | ki: 0.17nM |
| α2c-adrenergicreceptor | ki: 1.3nM |
| D2receptor | ki: 3.57nM |
| D3receptor | ki: 3.6nM |
| D2LReceptor | ki: 4.16nM |
| D4receptor | ki: 4.66nM |
| D2SReceptor | ki: 4.73nM |
| α1A-adrenergicreceptor | ki: 5nM |
| 5-HT7 | ki: 6.6nM |
| α1B-adrenergicreceptor | ki: 9nM |
| 5-HT2C | ki: 12nM |
| 5-HT1B | ki: 14.9nM |
| α2a-adrenergicreceptor | ki: 16.5nM |
| H1receptor | ki: 20.1nM |
| 5-HT2B | ki: 61.9nM |
| 5-HT1D | ki: 84.6nM |
| α2b-adrenergicreceptor | ki: 108nM |
| H2receptor | ki: 120nM |
| 5-HT5A | ki: 206nM |
| 5-HT5A | ki: 206nM |
| D1receptor | ki: 244nM |
| D5receptor | ki: 290nM |
| 5-HT1A | ki: 423nM |
| 5-HT6 | ki: 2060nM |
| In vitro | DMSO | 3 mg/mL (7.3 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 4 mg/mL (9.74 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.36 mL | 121.8 mL | 243.61 mL |
| 0.5 mM | 4.87 mL | 24.36 mL | 48.72 mL |
| 1 mM | 2.44 mL | 12.18 mL | 24.36 mL |
| 5 mM | 0.49 mL | 2.44 mL | 4.87 mL |
*The above data is based on the productmolecular weight 410.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A10797 |
|---|---|
| Actions | N/A |
| M. Wt | 410.5 |
| Formula | C23H27FN4O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 106266-06-2 |
| Synonyms | R 64 766, Risperdal |
| SMILES | CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F |
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