Total item
Cart Subtotal
$0.00 Black Friday & Year End Sale starting Nov 21st 2022 through Jan 2nd 2023, enjoy 20% off sitewide
- Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
- Jaime Osuna-Luque, .et al. Behavioral Mechanisms That Depend on Dopamine and Serotonin in Caenorhabditis elegans Interact With the Antipsychotics Risperidone and Aripiprazole, J Exp Neurosci, 2018, 12: 1179069518798628 PMID: 30245571
Biological Activity
Risperidone(Risperdal) is an atypical antipsychotic used to treat schizophrenia (including adolescent schizophrenia), schizoaffective disorder, the mixed and manic states associated with bipolar disorder, and irritability in children with autism.
Targets
| Target | Value |
|---|---|
| 5-HT2A | ki: 0.17nM |
| α2c-adrenergicreceptor | ki: 1.3nM |
| D2receptor | ki: 3.57nM |
| D3receptor | ki: 3.6nM |
| D2LReceptor | ki: 4.16nM |
| D4receptor | ki: 4.66nM |
| D2SReceptor | ki: 4.73nM |
| α1A-adrenergicreceptor | ki: 5nM |
| 5-HT7 | ki: 6.6nM |
| α1B-adrenergicreceptor | ki: 9nM |
| 5-HT2C | ki: 12nM |
| 5-HT1B | ki: 14.9nM |
| α2a-adrenergicreceptor | ki: 16.5nM |
| H1receptor | ki: 20.1nM |
| 5-HT2B | ki: 61.9nM |
| 5-HT1D | ki: 84.6nM |
| α2b-adrenergicreceptor | ki: 108nM |
| H2receptor | ki: 120nM |
| 5-HT5A | ki: 206nM |
| 5-HT5A | ki: 206nM |
| D1receptor | ki: 244nM |
| D5receptor | ki: 290nM |
| 5-HT1A | ki: 423nM |
| 5-HT6 | ki: 2060nM |
| In vitro | DMSO | Warmed: 4 mg/mL (9.74 mM) | |
| Water | Insoluble | ||
| Ethanol | 4 mg/mL (9.74 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.36 mL | 121.8 mL | 243.61 mL |
| 0.5 mM | 4.87 mL | 24.36 mL | 48.72 mL |
| 1 mM | 2.44 mL | 12.18 mL | 24.36 mL |
| 5 mM | 0.49 mL | 2.44 mL | 4.87 mL |
*The above data is based on the productmolecular weight 410.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10797 |
|---|---|
| CAS No. | 106266-06-2 |
| Formula | C23H27FN4O2 |
| M. Wt | 410.5 |
| Purity | >98% |
| Synonyms | R 64 766, Risperdal |
| SMILES | CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Datasheet
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy Risperidone (Risperdal) | Risperidone (Risperdal) Supplier | purchase | cost | manufacturer | order | distributor | buy 106266-06-2| 106266-06-2 Supplier | purchase 106266-06-2 | 106266-06-2 cost | 106266-06-2 manufacturer | order 106266-06-2 | 106266-06-2 distributor
Adooq Quality Guarantee
We promise all products perform as described.