Fig. 1 · Structure
Documents & Downloads
Rivanicline fumarate
nAChR Agonist
Rivanicline fumarate is a selective agonist of neuronal nicotinic acetylcholine receptors (nAChRs), primarily targeting the α4β2 subtype with a Ki of 26 nM and an EC50 of 16 μM. This compound has demonstrated the ability to significantly restore learning impairments and alleviate cognitive dysfunctions. Rivanicline fumarate is valuable in research focused on neurodegenerative diseases, including schizophrenia and Alzheimer's disease, providing insights into potential therapeutic approaches.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 183288-99-5 |
| Applications | nAChR Agonist |
| Formula | C14H18N2O4 |
| Molecular Weight | 278.30 |
| Synonyms | RJR-2403 fumarate; (E)-Metanicotine fumarate |
| SMILES | CNCC/C=C/C1=CC=CN=C1.O=C(O)/C=C/C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.