Fig. 1 · Structure
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RL-0070933
Smoothed Modulator
RL-0070933 is a potent Smoothened (SMO) modulator with an EC50 value of 0.02 µM. It influences the translocation and accumulation of Smoothened protein to primary cilia via the Hedgehog signaling pathway. This compound is primarily used in research applications targeting cellular signaling mechanisms and developmental biology, particularly in studies related to cancer and developmental disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 301326-41-0 |
| Applications | Smoothed Modulator |
| Formula | C20H16N2O2 |
| Molecular Weight | 316.35 |
| SMILES | O=C(N/N=C/C1=CC=C(C2=CC=CC=C2)C=C1)C3=CC=C(O)C=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.