Fig. 1 · Structure
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RMC-113
PIP4K2C/PIKfyve Inhibitor
RMC-113 is an inhibitor of PIP4K2C and PIKfyve, exhibiting Ki values of 46 nM and 370 nM, respectively. This compound effectively reverses SARS-CoV-2-induced impairment of autophagic flux, showcasing its potential as an antiviral agent. RMC-113 is valuable for research applications focused on viral pathogenesis and autophagy modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2258606-34-5 |
| Applications | PIP4K2C/PIKfyve Inhibitor |
| Formula | C21H15N3O2S |
| Molecular Weight | 373.43 |
| SMILES | COC1=C(OC)C=CC(C2=CC3=NSC(C#CC4=CC=CN=C4)=C3N=C2)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.