Fig. 1 · Structure
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RNase A, Bovine pancreas
Enzyme
RNase A, derived from bovine pancreas, is an endonuclease that specifically hydrolyzes cytosine and uracil residues in RNA. This enzyme is critical for RNA degradation in RNA/DNA duplexes and catalyzes the breakdown of 3',5'-phosphodiester linkages in single-stranded RNA. RNase A plays significant roles in various physiological and pathological processes such as cell growth, differentiation, and tumor cell cytotoxicity, with its dysregulation implicated in cancers of the pancreas, ovaries, bladder, and thyroid. This reagent is valuable for applications in molecular biology, including nucleic acid purification and cellular studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 9001-99-4 |
| Applications | Enzyme |
| Synonyms | Ribonuclease A; EC 4.6.1.18; RNase A |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.