Fig. 1 · Structure
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RNPA1000
RnpA Inhibitor
RNPA1000 is a selective RnpA inhibitor that effectively hinders RnpA-mediated RNA degradation in cells. This compound demonstrates an IC50 of 175 μM for the inhibition of tRNA maturation. RNPA1000 exhibits broad-spectrum antimicrobial properties, specifically targeting staphylococcal and various Gram-positive bacterial pathogens, making it a valuable tool for research in antimicrobial resistance and RNA biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 359600-10-5 |
| Applications | RnpA Inhibitor |
| Formula | C23H18BrN3O3 |
| Molecular Weight | 464.31 |
| SMILES | O=C(O)C1=CC=C(N2C(C)=C(/C=C(C#N)/C(NC3=CC=CC(Br)=C3)=O)C=C2C)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.